Exploring a Career Pivot from Big Tech

By fezzy🔸 @ 2025-10-10T02:00 (+8)

Context

I’m an EA working at a large tech company, with several years of experience in a niche technical stack (kept vague for anonymity). Over the past six months, I’ve been reflecting deeply on how to make my career more impactful. I’d love advice, connections, or even words of encouragement as I navigate this transition.

Cause Areas

I’m most drawn to biosecurity, though I remain open to alternative proteinsclimate and animal welfare (ranked in decreasing order of interest). My current sense is that the main bottlenecks in the latter two areas are policy-related rather than technical. I’ve mostly ruled out AI safety, since it feels saturated and somewhat misaligned with my background.

I’m most interested in pivoting to biosecurity, but I haven’t completely ruled out other cause areas such as climate or animal welfare. However, I do think that the bottleneck in both climate and animal welfare are more policy related than technical. I should probably mention that I’ve (mostly) ruled out AI Safety as a cause area because 1) I feel as though this area is saturated and 2) I lack relevant experience. 

Current Dilemmas

I’m not sure how to pivot to biosecurity. I could pivot to cybersecurity, and apply those skills to biosecurity down the line. I figured I could do an internal transfer to a cybersecurity role at my current company. However, even that has proved difficult, since most managers want someone with backend development experience. 

Also I’m having trouble splitting my time between interview prep, applying for jobs, and research cause areas.  Part of me wonders if I should quit my job to focus fully on the transition, but I’d prefer to have a clearer plan first.

Key Uncertainties

Call to Action

I would appreciate any advice at all, but here are some specific asks for anyone reading this


 

Appendix

Concrete steps/action items

Here’s a list of what I’ve done: 

 

Here’s a list of I plan to do, but just haven’t gotten around to do doing just yet


Toby Tremlett🔹 @ 2025-10-15T09:15 (+4)

@Swan 🔸 @Jeff Kaufman 🔸 
Any suggestions for next steps in biosecurity here/ what would you need to know from @fezzy🔸 to recommend next steps?

Jeff Kaufman 🔸 @ 2025-10-15T12:28 (+4)

@fezzy🔸 one important difference (especially important to me!) since we last talked is that the NAO just opened a position for a software engineer; consider applying? https://securebio.org/careers/bioinformatics-engineer-2025/

I wouldn't recommend getting into cybersecurity as a path to biosecurity.  From the outside, the main thing that transfers in the actual work is the mindset, but a very large majority of skills in both areas are domain specific.  On the other hand, I do think there are valuable things that need doing in cybersecurity, and biosecurity efforts nearly always also have cybersecurity needs.

fezzy🔸 @ 2025-10-21T18:22 (+1)

I just applied! Thank you for the insights and for connecting me with this opportunity